Judicious selection of stable isotopes and NMR spectroscopy allow us to study metabolic pathways and fluxes in vivo.
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Eunsook S. Jin, Ph.D., D.D.S.
Research Overview
The measurement of comprehensive metabolic fluxes in vivo is important in understanding pathophysiology of a metabolic disease such as diabetes. It is challenging, but stable
isotopes and NMR spectroscopy may allow us to study in vivo fluxes. My research interests are intermediary metabolism, obesity-associated type 2 diabetes, and glucose-fat
metabolic interaction using stable isotopes and NMR as key research tools. I have used animal models in studying intermediary metabolism and diabetes, but recently started
clinical research focusing on obesity-associated type 2 diabetes. The clinical study includes hyperinsulinemic euglycemic clamp technique and hepatic fat measurement using a
3T MR scanner in addition to multiple stable isotope administration and NMR spectroscopic analysis.
Contact email: eunsook.jin@utsouthwestern.edu
Research Interests
| Intermediary metabolism | NMR |
| Insulin resistance & Type 2 diabetes | Glucose-fat metabolic interaction |
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